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2012•Biology Bulletin ReviewsRequires access

Endothelial progenitor cells and neovasculogenesis

О. В. Повещенко, А. Ф. Повещенко, В. И. Коненков

Open publisher page 5 citations

Abstract

It is has been established that endothelial progenitor cells EPC are of great interest in the maintenance of endothelial integrity and postnatal neovascularization of the adult organism’s tissues. It is shown that the formation of new blood vessels can be carried out both by angiogenesis and vasculogenesis from EPC. In this review, data are presented on the heterogeneity of the EPC in population. These cells are indentified by different markers and have different proliferative and functional capacities. They not only activate the neovascularization of tissues after damage, but also they are potential candidates for therapeutic angiogenesis.

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What this paper is about

It is has been established that endothelial progenitor cells EPC are of great interest in the maintenance of endothelial integrity and postnatal neovascularization of the adult organism’s tissues. It is shown that the formation of new blood vessels can be carried out both by angiogenesis and vasculogenesis from EPC. In this review, data are presented on the heterogeneity of the EPC in population. These cells are indentified by different markers and have different proliferative and functional capacities. They not only activate the neovascularization of tissues after damage, but also they are potential candidates for therapeutic angiogenesis.

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OpenAlex reports 5 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

It is has been established that endothelial progenitor cells EPC are of great interest in the maintenance of endothelial integrity and postnatal neovascularization of the adult organism’s tissues. It is shown that the formation of new blood vessels can be carried out both by angiogenesis and vasculogenesis from EPC. In this review, data are presented on the heterogeneity of the EPC in population. These cells are indentified by different markers and have different proliferative and functional capacities. They not only activate the neovascularization of tissues after damage, but also they are potential candidates for therapeutic angiogenesis.

Key concepts: Vasculogenesis, Neovascularization, Biology, Angiogenesis, Progenitor cell, Population, Cell biology, Progenitor

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