2003New England Journal of MedicineRequires access

Molecular Mimicry in Multiple Sclerosis

Hartmut Wekerle, Reinhard Hohlfeld

Open publisher page 68 citations

Abstract

Molecular mimicry is a model in which foreign antigens are sufficiently similar to native antigens to trigger an autoimmune response. A study involving the specificity of a T-cell receptor derived from a patient with multiple sclerosis indicates that molecular mimicry extends to complexes of proteins — a finding with implications for therapy.

About this research paper

What this paper is about

Molecular mimicry is a model in which foreign antigens are sufficiently similar to native antigens to trigger an autoimmune response. A study involving the specificity of a T-cell receptor derived from a patient with multiple sclerosis indicates that molecular mimicry extends to complexes of proteins — a finding with implications for therapy.

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OpenAlex reports 68 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Molecular mimicry is a model in which foreign antigens are sufficiently similar to native antigens to trigger an autoimmune response. A study involving the specificity of a T-cell receptor derived from a patient with multiple sclerosis indicates that molecular mimicry extends to complexes of proteins — a finding with implications for therapy.

Key concepts: Mimicry, Molecular mimicry, Multiple sclerosis, Medicine, Antigen, Immunology, Biology, Zoology

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