Molecular Mimicry in Multiple Sclerosis
Hartmut Wekerle, Reinhard Hohlfeld
Abstract
Hartmut Wekerle, Reinhard Hohlfeld
Abstract
Molecular mimicry is a model in which foreign antigens are sufficiently similar to native antigens to trigger an autoimmune response. A study involving the specificity of a T-cell receptor derived from a patient with multiple sclerosis indicates that molecular mimicry extends to complexes of proteins — a finding with implications for therapy.
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Molecular mimicry is a model in which foreign antigens are sufficiently similar to native antigens to trigger an autoimmune response. A study involving the specificity of a T-cell receptor derived from a patient with multiple sclerosis indicates that molecular mimicry extends to complexes of proteins — a finding with implications for therapy.
Key concepts: Mimicry, Molecular mimicry, Multiple sclerosis, Medicine, Antigen, Immunology, Biology, Zoology