1947New England Journal of MedicineRequires access

The Detection of Tubercle Bacilli by Fluorescence Microscopy

Leon Levinson, Ronald L. White

Open publisher page 3 citations

Abstract

THE method of fluorescent staining for the demonstration of tubercle bacilli in smears proposed in 1937 by Hagemann1 offered a promising simplification of the rather cumbersome Ziehl—Neelsen technic. Many in this country have tried the procedure and have not been impressed with the results.2 The objections are in some cases due to insufficient trial and in others to inadequate equipment. Better methods have now been developed, and it is the purpose of this paper to outline the technic and equipment and the results obtained therewith.The tubercle bacillus does not fluoresce of its own accord but can be made to . . .

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THE method of fluorescent staining for the demonstration of tubercle bacilli in smears proposed in 1937 by Hagemann1 offered a promising simplification of the rather cumbersome Ziehl—Neelsen technic. Many in this country have tried the procedure and have not been impressed with the results.2 The objections are in some cases due to insufficient trial and in others to inadequate equipment. Better methods have now been developed, and it is the purpose of this paper to outline the technic and equipment and the results obtained therewith.The tubercle bacillus does not fluoresce of its own accord but can be made to . . .

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Available abstract

THE method of fluorescent staining for the demonstration of tubercle bacilli in smears proposed in 1937 by Hagemann1 offered a promising simplification of the rather cumbersome Ziehl—Neelsen technic. Many in this country have tried the procedure and have not been impressed with the results.2 The objections are in some cases due to insufficient trial and in others to inadequate equipment. Better methods have now been developed, and it is the purpose of this paper to outline the technic and equipment and the results obtained therewith.The tubercle bacillus does not fluoresce of its own accord but can be made to . . .

Key concepts: Tubercle, Bacilli, Fluorescent staining, Bacillus (shape), Medicine, Staining, Pathology, Microbiology

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