2011•Nature Structural & Molecular BiologyOpen access

Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant α-1 antitrypsin from the endoplasmic reticulum

Ethan J. Greenblatt, James A. Olzmann, Ron R. Kopito

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Key concepts: Rhomboid, Endoplasmic-reticulum-associated protein degradation, Endoplasmic reticulum, AAA proteins, Cell biology, Cytoplasm, Ubiquitin, Proteases

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Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant α-1 antitrypsin from the endoplasmic reticulum — Research Paper | ScholarLens