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Mismatch Between lodine-123 IMP and Technetium-99m HM-PAO Brain Perfusion Imaging in a Patient with Meningioma

Hiroaki Hoshi, SEISHI JINNOUCHI, Katsushi Watanabe, Shin‐ichi Nakano, KAZUO KINSHITA

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Abstract

The discrepancy between three methods for cerebral perfusion imagings in the case of a man with meningioma is presented. Imaging with N-isopropyl-P-[I-123] iodoamphetamine (IMP) showed no activity in the tumor. Imaging with Tc-99m hexamethylpropyleneamine oxime (HM-PAO) and the local cerebral blood flow (LCBF) image with Xe-133 inhalation showed high tumor activity. IMP is a more accurate method for imaging the brain tissue blood flow.

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What this paper is about

The discrepancy between three methods for cerebral perfusion imagings in the case of a man with meningioma is presented. Imaging with N-isopropyl-P-[I-123] iodoamphetamine (IMP) showed no activity in the tumor. Imaging with Tc-99m hexamethylpropyleneamine oxime (HM-PAO) and the local cerebral blood flow (LCBF) image with Xe-133 inhalation showed high tumor activity. IMP is a more accurate method for imaging the brain tissue blood flow.

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Available abstract

The discrepancy between three methods for cerebral perfusion imagings in the case of a man with meningioma is presented. Imaging with N-isopropyl-P-[I-123] iodoamphetamine (IMP) showed no activity in the tumor. Imaging with Tc-99m hexamethylpropyleneamine oxime (HM-PAO) and the local cerebral blood flow (LCBF) image with Xe-133 inhalation showed high tumor activity. IMP is a more accurate method for imaging the brain tissue blood flow.

Key concepts: Medicine, Cerebral blood flow, Nuclear medicine, Technetium, Meningioma, Perfusion, Blood flow, Perfusion scanning

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Mismatch Between lodine-123 IMP and Technetium-99m HM-PAO Brain Perfusion Imaging in a Patient with Meningioma — Research Paper | ScholarLens