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Osteonecrosis in sickle cell trait.

Taylor Pw, Thorpe Wp, Trueblood Mc

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Abstract

Osteonecrosis is common in sickle cell anemia but has been rarely reported with sickle cell trait. Two cases of osteonecrosis of the femoral head caused by sickle cell trait are presented. One patient's diagnosis was delayed because the association of osteonecrosis and sickle cell trait was not recognized. The previous reported cases of this association are discussed, emphasizing diagnostic implications for 12 black patients presenting with hip pain.

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What this paper is about

Osteonecrosis is common in sickle cell anemia but has been rarely reported with sickle cell trait. Two cases of osteonecrosis of the femoral head caused by sickle cell trait are presented. One patient's diagnosis was delayed because the association of osteonecrosis and sickle cell trait was not recognized. The previous reported cases of this association are discussed, emphasizing diagnostic implications for 12 black patients presenting with hip pain.

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OpenAlex reports 17 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Osteonecrosis is common in sickle cell anemia but has been rarely reported with sickle cell trait. Two cases of osteonecrosis of the femoral head caused by sickle cell trait are presented. One patient's diagnosis was delayed because the association of osteonecrosis and sickle cell trait was not recognized. The previous reported cases of this association are discussed, emphasizing diagnostic implications for 12 black patients presenting with hip pain.

Key concepts: Medicine, Sickle cell trait, Sickle cell anemia, Hemoglobinopathy, Femoral head, Hip pain, Trait, Internal medicine

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