ChemInform Abstract: Furan Ring Opening—Pyrrole Ring Closure: Simple Route to 5‐Alkyl‐2‐(aminomethyl)pyrroles.
А. В. Бутин, Tatyana A. Nevolina, Vitaly A. Shcherbinin, Maxim G. Uchuskin, Olga V. Serdyuk, Igor V. Trushkov
Abstract
А. В. Бутин, Tatyana A. Nevolina, Vitaly A. Shcherbinin, Maxim G. Uchuskin, Olga V. Serdyuk, Igor V. Trushkov
Abstract
Abstract The synthesis of the title pyrroles is based on hydrolytic ring opening of substrates (I) followed by pyrrole ring closure of ketones (II) under Paal—Knorr conditions.
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Abstract The synthesis of the title pyrroles is based on hydrolytic ring opening of substrates (I) followed by pyrrole ring closure of ketones (II) under Paal—Knorr conditions.
Key concepts: Chemistry, Furan, Pyrrole, Ring (chemistry), Closure (psychology), Alkyl, Simple (philosophy), Medicinal chemistry