2008Bioorganic & Medicinal Chemistry LettersRequires access

Orally bioavailable prodrugs of a BCS class 2 molecule, an inhibitor of HIV-1 reverse transcriptase

Todd R. Elworthy, James P. Dunn, J. Heather Hogg, Grace Lam, Yoshio Saitō, Tania M.P.C. Silva, Dimitrios Stefanidis, Witold Woroniecki, Eugenia Zhornisky, Amy S. Zhou, Klaus Klumpp

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Key concepts: Prodrug, Chemistry, Hydroxymethyl, Bioavailability, Reverse transcriptase, Chemical synthesis, Pharmacokinetics, Reverse-transcriptase inhibitor

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