VALUE OF TOXOPLASMA GONDII DETECTION IN ONE HUNDRED THIRTY-THREE PLACENTAS FOR THE DIAGNOSIS OF CONGENITAL TOXOPLASMOSIS
Hélène Fricker‐Hidalgo, Marie‐Pierre Brenier‐Pinchart, Jean Patrick Schaal, V. Equy, Cécile Bost-Bru, Hervé Pelloux
Abstract
Hélène Fricker‐Hidalgo, Marie‐Pierre Brenier‐Pinchart, Jean Patrick Schaal, V. Equy, Cécile Bost-Bru, Hervé Pelloux
Abstract
The placenta examination by polymerase chain reaction and mouse inoculation increased the sensitivity of the diagnosis of congenital toxoplasmosis at birth from 60% (use of serologic techniques on the newborn's blood only) to 75% (both serologic techniques and placental analysis). The specificity of Toxoplasma gondii detection in the placenta was 94.7%.
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The placenta examination by polymerase chain reaction and mouse inoculation increased the sensitivity of the diagnosis of congenital toxoplasmosis at birth from 60% (use of serologic techniques on the newborn's blood only) to 75% (both serologic techniques and placental analysis). The specificity of Toxoplasma gondii detection in the placenta was 94.7%.
Key concepts: Toxoplasmosis, Toxoplasma gondii, Placenta, Serology, Polymerase chain reaction, Medicine, Congenital toxoplasmosis, Obstetrics