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1966•Psychological ReportsRequires access

Retrograde Amnesia in Two Strains of Mice

Richard L. Sprott

Open publisher page 4 citations

Abstract

The administration of electroconvulsive shock after foot shock in a passive avoidance learning situation produced retrograde amnesia if electroconvulsive shock occurred within 20 sec. of the foot shock. If the time interval between foot shock and electroconvulsive shock was 20 sec. or longer, retrograde amnesia was not observed. No behavioral differences were observed between two inbred strains of mice, the DBA/2J and the C57BL/6J.

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What this paper is about

The administration of electroconvulsive shock after foot shock in a passive avoidance learning situation produced retrograde amnesia if electroconvulsive shock occurred within 20 sec. of the foot shock. If the time interval between foot shock and electroconvulsive shock was 20 sec. or longer, retrograde amnesia was not observed. No behavioral differences were observed between two inbred strains of mice, the DBA/2J and the C57BL/6J.

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Available abstract

The administration of electroconvulsive shock after foot shock in a passive avoidance learning situation produced retrograde amnesia if electroconvulsive shock occurred within 20 sec. of the foot shock. If the time interval between foot shock and electroconvulsive shock was 20 sec. or longer, retrograde amnesia was not observed. No behavioral differences were observed between two inbred strains of mice, the DBA/2J and the C57BL/6J.

Key concepts: Electroconvulsive Shock, Retrograde amnesia, Amnesia, Psychology, Shock (circulatory), Electroconvulsive therapy, Anesthesia, Neuroscience

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