1993•GenomicsOpen access

Characterization of Microsatellite Polymorphisms DXS691 and DXS692: Genetic Mapping to Xq26.2-Xq27 and Xq25-Xq26.2

Daniel M. Lasser, Kirk C. Wilhelmsen, Torbjoern G. Nygaard, Umadevi Tantravahi

Abstract

Simple sequence repeat microsatellite polymorphisms are extremely useful markers for resolutional enhancement of human genetic linkage maps due to the existence of multiple alleles and a high degree of heterozygosity. The authors have identified and characterized two polymorphic CA-dinucleotide repeats and have determined their positional assignment on the X chromosome by genetic and physical mapping. 14 refs., 1 tab.

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Available abstract

Key concepts: Microsatellite, Biology, Loss of heterozygosity, Genetics, Gene mapping, Genetic linkage, Dinucleotide Repeat, X chromosome