2010Journal of Nippon Medical SchoolOpen access

Controversy of Corticosteroids in Septic Shock

Masao Miyashita

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Abstract

The mortality rate of septic shock remains high. The guidelines of the Surviving Sepsis Campaign were published in 2004 and were revised in 2008. Steroid therapy is prominent in the guidelines but remains controversial. In this review, steroid therapy for septic shock is discussed with various landmark papers.

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The mortality rate of septic shock remains high. The guidelines of the Surviving Sepsis Campaign were published in 2004 and were revised in 2008. Steroid therapy is prominent in the guidelines but remains controversial. In this review, steroid therapy for septic shock is discussed with various landmark papers.

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Available abstract

The mortality rate of septic shock remains high. The guidelines of the Surviving Sepsis Campaign were published in 2004 and were revised in 2008. Steroid therapy is prominent in the guidelines but remains controversial. In this review, steroid therapy for septic shock is discussed with various landmark papers.

Key concepts: Septic shock, Medicine, Shock (circulatory), Sepsis, Intensive care medicine, Surviving Sepsis Campaign, Mortality rate, Shock therapy

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