C-Mitosis Without Colchicine in Human Leucocyte Cultures

Observations in the present study have shown a 2.8±0.141 percent incidence of supercontracted metaphases derived from human short-term leucocyte cultures. It is apparent that a type of C-mitosis exists in short-term human leucocyte cul-tures as indicated by the occurrence of C-pairs, by the occurrence of diplo-chromo-somes, and by an indication of the beginning of C-anaphase. Furthermore the occurrence of many scattered supercontracted metaphases can be taken as an indi-cation of C-mitosis. Anaphases derived from both normal and supercontracted metaphases are apparently asynchronous for centromeric separation.