2013•Anti-Cancer Agents in Medicinal ChemistryRequires access

Betulin-Betulinic Acid Natural Product Based Analogs as Anti-Cancer Agents

Subash C. Jonnalagadda, Michael A. Corsello, Christopher E. Sleet

Abstract

Herein we describe a brief account of betulin and betulinic acid: two natural products isolated from birch bark, their chemical modifications and further biological/medicinal applications. Keywords: Natural products, terpenes, lupanes, triterpenoids, birch bark, betulin, betulinic acid, anti-cancer agents.

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Key concepts: Betulinic acid, Betulin, Bark (sound), Natural product, Terpene, Chemistry, Triterpenoid, Traditional medicine