1998•Bioscience Biotechnology and BiochemistryRequires access

6-Methylsulfinylhexyl Isothiocyanate and Its Homologues as Food-originated Compounds with Antibacterial Activity againstEscherichia coliandStaphylococcus aureus

Haruhiro Ono, Shoko Tesaki, Soichi Tanabe, Michiko Watanabe

Abstract

Cruciferae plants, banana and coriander each showed antibacterial activity. The highest activity among the food-stuffs tested was found in the stems of wasabi. An ethereal extract from wasabi stems had potent antibacterial activity and we isolated the active compound from the extract. Instrumental analysis identified the compound as 6-methylsulfinylhexyl isothiocyanate. Some homologues of 6-methylsulfinylhexyl isothiocyanate were also active against Escherichia coli and Staphylococcus aureus.

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Key concepts: Staphylococcus aureus, Antibacterial activity, Escherichia coli, Isothiocyanate, Allyl isothiocyanate, Chemistry, Food science, Microbiology