2008•Bioorganic & Medicinal Chemistry LettersOpen access

α-Mercaptoketone based histone deacetylase inhibitors

Paul L. Wash, Timothy Z. Hoffman, Brandon M. Wiley, Céline Bonnefous, Nicholas D. Smith, Michael S. Sertic, Charles Martin Lawrence, Kent T. Symons, Phan-Manh Nguyen, Kevin D. Lustig, Xin Guo, Tami Annable, Stewart A. Noble, Jeffrey H. Hager, Christian A. Hassig, James W. Malecha

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Key concepts: Chemistry, Histone deacetylase, Histone deacetylase inhibitor, Enzyme inhibitor, Histone, Pharmacology, Stereochemistry, Biochemistry