2015•The Journal of UrologyRequires access

Uncovering the Metabolic Complications of Androgen Deprivation Therapy in Patients with Prostate Cancer—Where Do We Take it Next?

Jehonathan H. Pinthus

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Abstract

No AccessJournal of UrologyEditorial1 Jun 2015Uncovering the Metabolic Complications of Androgen Deprivation Therapy in Patients with Prostate Cancer—Where Do We Take it Next? Jehonathan H. Pinthus Jehonathan H. PinthusJehonathan H. Pinthus More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.03.070AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Uncovering the Metabolic Complications of Androgen Deprivation Therapy in Patients with Prostate Cancer—Where Do We Take it Next?." The Journal of Urology, 193(6), pp. 1882–1883 References 1 : Risk of diabetes among patients receiving primary androgen deprivation therapy for clinically localized prostate cancer. J Urol2015; 193: 1956. Link, Google Scholar 2 : The metabolic syndrome and its components in patients with prostate cancer on androgen deprivation therapy. J Urol2015; 193: 1963. Link, Google Scholar 3 : Association between androgen-deprivation therapy and incidence of diabetes among males with prostate cancer. Urology2007; 70: 1104. Google Scholar 4 : Diabetes and cardiovascular disease during androgen deprivation therapy for prostate cancer. J Clin Oncol2006; 24: 4448. Google Scholar 5 : Metabolic syndrome in men with prostate cancer undergoing long-term androgen-deprivation therapy. J Clin Oncol2006; 24: 3979. Google Scholar 6 : Standards of medical care in diabetes–2014. Diabetes Care2014; 37: S14. Google Scholar 7 : The effects of induced hypogonadism on arterial stiffness, body composition, and metabolic parameters in males with prostate cancer. J Clin Endocrinol Metab2001; 86: 4261. Crossref, Medline, Google Scholar 8 : The effect of androgen deprivation therapy on body composition in men with prostate cancer: systematic review and meta-analysis. J Cancer Surviv2010; 4: 128. Google Scholar 9 : Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy. N Engl J Med1990; 322: 223. Google Scholar 10 : Exercise-induced reversal of insulin resistance in obese elderly is associated with reduced visceral fat. J Appl Physiol (1985)2006; 100: 1584. Google Scholar 11 : Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med2002; 346: 393. Google Scholar 12 : GnRH antagonist associates with less adiposity and reduced characteristics of metabolic syndrome and atherosclerosis compared with orchiectomy and GnRH agonist in a preclinical mouse model. Urol Oncol2014; 32: 1126. Google Scholar © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 6June 2015Page: 1882-1883 Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Jehonathan H. Pinthus More articles by this author Expand All Advertisement PDF downloadLoading ...

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No AccessJournal of UrologyEditorial1 Jun 2015Uncovering the Metabolic Complications of Androgen Deprivation Therapy in Patients with Prostate Cancer—Where Do We Take it Next? Jehonathan H. Pinthus Jehonathan H. PinthusJehonathan H. Pinthus More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.03.070AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Uncovering the Metabolic Complications of Androgen Deprivation Therapy in Patients with Prostate Cancer—Where Do We Take it Next?." The Journal of Urology, 193(6), pp. 1882–1883 References 1 : Risk of diabetes among patients receiving primary androgen deprivation therapy for clinically localized prostate cancer. J Urol2015; 193: 1956. Link, Google Scholar 2 : The metabolic syndrome and its components in patients with prostate cancer on androgen deprivation therapy. J Urol2015; 193: 1963. Link, Google Scholar 3 : Association between androgen-deprivation therapy and incidence of diabetes among males with prostate cancer. Urology2007; 70: 1104. Google Scholar 4 : Diabetes and cardiovascular disease during androgen deprivation therapy for prostate cancer. J Clin Oncol2006; 24: 4448. Google Scholar 5 : Metabolic syndrome in men with prostate cancer undergoing long-term androgen-deprivation therapy. J Clin Oncol2006; 24: 3979. Google Scholar 6 : Standards of medical care in diabetes–2014. Diabetes Care2014; 37: S14. Google Scholar 7 : The effects of induced hypogonadism on arterial stiffness, body composition, and metabolic parameters in males with prostate cancer. J Clin Endocrinol Metab2001; 86: 4261. Crossref, Medline, Google Scholar 8 : The effect of androgen deprivation therapy on body composition in men with prostate cancer: systematic review and meta-analysis. J Cancer Surviv2010; 4: 128. Google Scholar 9 : Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy. N Engl J Med1990; 322: 223. Google Scholar 10 : Exercise-induced reversal of insulin resistance in obese elderly is associated with reduced visceral fat. J Appl Physiol (1985)2006; 100: 1584. Google Scholar 11 : Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med2002; 346: 393. Google Scholar 12 : GnRH antagonist associates with less adiposity and reduced characteristics of metabolic syndrome and atherosclerosis compared with orchiectomy and GnRH agonist in a preclinical mouse model. Urol Oncol2014; 32: 1126. Google Scholar © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 6June 2015Page: 1882-1883 Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Jehonathan H. Pinthus More articles by this author Expand All Advertisement PDF downloadLoading ...

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Available abstract

No AccessJournal of UrologyEditorial1 Jun 2015Uncovering the Metabolic Complications of Androgen Deprivation Therapy in Patients with Prostate Cancer—Where Do We Take it Next? Jehonathan H. Pinthus Jehonathan H. PinthusJehonathan H. Pinthus More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.03.070AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Uncovering the Metabolic Complications of Androgen Deprivation Therapy in Patients with Prostate Cancer—Where Do We Take it Next?." The Journal of Urology, 193(6), pp. 1882–1883 References 1 : Risk of diabetes among patients receiving primary androgen deprivation therapy for clinically localized prostate cancer. J Urol2015; 193: 1956. Link, Google Scholar 2 : The metabolic syndrome and its components in patients with prostate cancer on androgen deprivation therapy. J Urol2015; 193: 1963. Link, Google Scholar 3 : Association between androgen-deprivation therapy and incidence of diabetes among males with prostate cancer. Urology2007; 70: 1104. Google Scholar 4 : Diabetes and cardiovascular disease during androgen deprivation therapy for prostate cancer. J Clin Oncol2006; 24: 4448. Google Scholar 5 : Metabolic syndrome in men with prostate cancer undergoing long-term androgen-deprivation therapy. J Clin Oncol2006; 24: 3979. Google Scholar 6 : Standards of medical care in diabetes–2014. Diabetes Care2014; 37: S14. Google Scholar 7 : The effects of induced hypogonadism on arterial stiffness, body composition, and metabolic parameters in males with prostate cancer. J Clin Endocrinol Metab2001; 86: 4261. Crossref, Medline, Google Scholar 8 : The effect of androgen deprivation therapy on body composition in men with prostate cancer: systematic review and meta-analysis. J Cancer Surviv2010; 4: 128. Google Scholar 9 : Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy. N Engl J Med1990; 322: 223. Google Scholar 10 : Exercise-induced reversal of insulin resistance in obese elderly is associated with reduced visceral fat. J Appl Physiol (1985)2006; 100: 1584. Google Scholar 11 : Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med2002; 346: 393. Google Scholar 12 : GnRH antagonist associates with less adiposity and reduced characteristics of metabolic syndrome and atherosclerosis compared with orchiectomy and GnRH agonist in a preclinical mouse model. Urol Oncol2014; 32: 1126. Google Scholar © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 6June 2015Page: 1882-1883 Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Jehonathan H. Pinthus More articles by this author Expand All Advertisement PDF downloadLoading ...

Key concepts: Androgen deprivation therapy, Prostate cancer, Medicine, Diabetes mellitus, Internal medicine, Androgen, Metabolic syndrome, Oncology

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