2011•Biophysical JournalOpen access

Identification and Biophysical Characterization of a Compound that Protects HERG from Block by a Proarrhythmic Agent

F Potet, Sébastien Chaigne, H. Irene Corey, Lewis Michelle, Engers Darren, Zhou Beiyan, Balser R. Jeffrey, Li Min, Lindsley Craig, Weaver David, Sabina Kupershmidt

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Key concepts: hERG, Dofetilide, Chemistry, Pharmacology, Potassium channel blocker, Repolarization, Cardiotoxicity, Biophysics

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Identification and Biophysical Characterization of a Compound that Protects HERG from Block by a Proarrhythmic Agent — Research Paper | ScholarLens