1988•Tissue AntigensRequires access

Characterization of a new murine monoclonal antibody against human DP antigens

V. Hořwší, Branko Chorvath, Katarína Poláková, Jozef Duraj, J Sedlák, Mária Karpatová

Abstract

Murine Hybridoma cell line BraFB6 was prepared producing monoclonal antibody reactive with an antigen identified as DP. This identification is based on the results of immunoprecipitation from radiolabeled cell lysates, competitive binding-inhibition assay with a reference anti-DP antibody B7/21, sequential immunoprecipitation and specific binding to the purified DP glycoprotein. In addition to this anti-DP monoclonal antibody, two anti-DR and two anti-DR +DP monoclonals were obtained.

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Available abstract

Key concepts: Monoclonal antibody, Antigen, Biology, Virology, Molecular biology, Antibody, Immunology