RENAL ISCHEMIA PRODUCED BY ANEURYSM OF ABDOMINAL AORTA

The experimental investigations of Goldblatt and his associates1on dogs in producing renal ischemia and an accompanying hypertensive vascular disease, either benign or malignant, have facilitated a better correlation of pathologic conditions observed in man in which renal ischemia has been produced by involvement of or alterations in the renal artery. The initial studies on experimental hypertension by Goldblatt and his co-workers demonstrated that constriction of the main renal artery of one kidney was followed by an elevation in blood pressure, which usually, but not always, returned to normal within four to eight weeks unless the artery to the other kidney was constricted or the other kidney removed. However, a few cases of hypertension in man have been observed and reported in which a constricting lesion of one renal artery has apparently been responsible for the coexisting hypertensive vascular disease. Hypertension has been reported in unilateral atherosclerotic narrowing2