1992•Microbiology and ImmunologyOpen access

The Protective Activity of Tea Catechins against Experimental Infection by Vibrio cholerae O1

Masako Toda, Sachie Okubo, Hajime Ikigai, Tatsuo Suzuki, Yumiko Suzuki, Yukihiko Hara, Tadakatsu Shimamura

Abstract

Tea catechins inhibited the fluid accumulation induced by cholera toxin in sealed adult mice. The catechins also reduced fluid accumulation by Vibrio cholerae O1 in ligated intestinal loops of rabbits. These findings suggest that tea catechins may possess protective activity against V. cholerae O1.

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Key concepts: Vibrio cholerae, Cholera toxin, Vibrionaceae, Cholera, Toxin, Microbiology, Biology, Catechin