2014•Neurobiology of DiseaseOpen access

Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits

Shababa T. Masoud, Laura M. Vecchio, Y. Bergeron, Muhammad M. Hossain, Long Nguyen, Marie Kristel Bermejo, Brian M. Kile, T.D. Sotnikova, William B. Siesser, Raul R. Gainetdinov, R. Mark Wightman, Marc G. Caron, Jason R. Richardson, Gary W. Miller, Amy J. Ramsey, Michel Cyr, Ali Salahpour

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Key concepts: Dopamine transporter, Dopamine, Dopaminergic, Dopamine Plasma Membrane Transport Proteins, Striatum, Chemistry, Dopamine Uptake Inhibitors, Neurotransmitter