The P‐Component of Amyloid of Human Islets of Langerhans
Per Westermark, M Skinner, Alan S. Cohen
Abstract
Per Westermark, M Skinner, Alan S. Cohen
Abstract
The P-component of amyloid was found in extracts of pancreases with islet amyloidosis. In double immunodiffusion this P-component showed lines of identity with isolated purified human P-component, normal human serum, and an extract of amyloid-rich liver tissue from a patient with primary systemic amyloidosis. The finding supports the theory that the P-component is present in all native human amyloid irrespective of type.
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The P-component of amyloid was found in extracts of pancreases with islet amyloidosis. In double immunodiffusion this P-component showed lines of identity with isolated purified human P-component, normal human serum, and an extract of amyloid-rich liver tissue from a patient with primary systemic amyloidosis. The finding supports the theory that the P-component is present in all native human amyloid irrespective of type.
Key concepts: Serum amyloid P component, Amyloid (mycology), Islet, Immunodiffusion, Amyloidosis, Component (thermodynamics), Human liver, Amyloid fibril