Development of water-soluble sono/photo-sensitive nanopartices for cancer treatment
Yongde Meng, Chunpu Zou, Min Huang, Jie Chen, James Z. Xing
Abstract
Yongde Meng, Chunpu Zou, Min Huang, Jie Chen, James Z. Xing
Abstract
Sonodyanmic Therapy (SDT) is a new type of cancer therapy and has attracted lots of research attention recently. In this article, we present how nano-formulation helped SL052 to form a water soluble sono/photo-sensitize nanoparticle (SL052-NPs) for cancer treatment. The nanostructure formation encapsulates SL052 and greatly improves the SL052 physicochemical properties without modifying its chemical structure. Nano-formulation also helps SL052 to achieve deep-site cancer delivery, image function for diagnosis, and ultrasound or photo controlled localized cancer therapy.
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Sonodyanmic Therapy (SDT) is a new type of cancer therapy and has attracted lots of research attention recently. In this article, we present how nano-formulation helped SL052 to form a water soluble sono/photo-sensitize nanoparticle (SL052-NPs) for cancer treatment. The nanostructure formation encapsulates SL052 and greatly improves the SL052 physicochemical properties without modifying its chemical structure. Nano-formulation also helps SL052 to achieve deep-site cancer delivery, image function for diagnosis, and ultrasound or photo controlled localized cancer therapy.
Key concepts: Cancer therapy, Cancer treatment, Cancer, Nanotechnology, Nanoparticle, Materials science, Nanostructure, Water soluble