1997•Biochemical PharmacologyRequires access

Biochemical and antiproliferative properties of 4-[Ar(alk)ylamino]pyridopyrimidines, a new chemical class of potent and specific epidermal growth factor receptor tyrosine kinase inhibitor

David W. Fry, James M. Nelson, Veronika Slintak, Paul R. Keller, Gordon W. Rewcastle, William A. Denny, Hairong Zhou, Alexander J. Bridges

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Key concepts: Autophosphorylation, A431 cells, Epidermal growth factor, Tyrosine kinase, Biology, Growth factor receptor, Epidermal growth factor receptor, Receptor tyrosine kinase