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2013•Leukemia & lymphoma/Leukemia and lymphomaRequires access

NovelNPM1mutation in the 3’-untranslated region identified in two patients with acute myeloid leukemia

Ajay Abraham, Sreeja Karathedath, Vinodhini Kumaraswamy, Ashok Kumar Jayavelu, Sathya Mani, Vivi M. Srivastava, Wei Zhang, Tong Zhou, Biju George, Alok Srivastava, Vikram Mathews, Poonkuzhali Balasubramanian

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Abstract

Nucleophosmin (NPM1) gene mutations are among the most studied genetic lesions in acute myeloid leukemia (AML) and are associated with a good prognosis. The frequency of exon 12 NPM1 mutation in ad...

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Nucleophosmin (NPM1) gene mutations are among the most studied genetic lesions in acute myeloid leukemia (AML) and are associated with a good prognosis. The frequency of exon 12 NPM1 mutation in ad...

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Available abstract

Nucleophosmin (NPM1) gene mutations are among the most studied genetic lesions in acute myeloid leukemia (AML) and are associated with a good prognosis. The frequency of exon 12 NPM1 mutation in ad...

Key concepts: NPM1, Myeloid leukemia, Mutation, Cancer research, Medicine, Untranslated region, Myeloid, Genetics

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