2014•The Pediatric Infectious Disease JournalRequires access

Fecal Microbiota Transplantation in Children With Recurrent Clostridium difficile Infection

Anne A. Pierog, Ali Mencin, Norelle Rizkalla Reilly

Open publisher page 40 citations

Abstract

Clostridium difficile eradication using fecal microbiota transplantation (FMT) has been successful in adults but little information is available in pediatrics. We report 6 pediatric patients with refractory C. difficile cured by FMT with no recurrences to date. Our results demonstrate that FMT can be an effective treatment for refractory C. difficile infection in pediatrics. Long-term safety and efficacy need to be studied.

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What this paper is about

Clostridium difficile eradication using fecal microbiota transplantation (FMT) has been successful in adults but little information is available in pediatrics. We report 6 pediatric patients with refractory C. difficile cured by FMT with no recurrences to date. Our results demonstrate that FMT can be an effective treatment for refractory C. difficile infection in pediatrics. Long-term safety and efficacy need to be studied.

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OpenAlex reports 40 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Clostridium difficile eradication using fecal microbiota transplantation (FMT) has been successful in adults but little information is available in pediatrics. We report 6 pediatric patients with refractory C. difficile cured by FMT with no recurrences to date. Our results demonstrate that FMT can be an effective treatment for refractory C. difficile infection in pediatrics. Long-term safety and efficacy need to be studied.

Key concepts: Clostridium difficile, Fecal bacteriotherapy, Refractory (planetary science), Feces, Medicine, C difficile, Transplantation, Microbiology

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