Fecal Microbiota Transplantation in Children With Recurrent Clostridium difficile Infection
Anne A. Pierog, Ali Mencin, Norelle Rizkalla Reilly
Abstract
Anne A. Pierog, Ali Mencin, Norelle Rizkalla Reilly
Abstract
Clostridium difficile eradication using fecal microbiota transplantation (FMT) has been successful in adults but little information is available in pediatrics. We report 6 pediatric patients with refractory C. difficile cured by FMT with no recurrences to date. Our results demonstrate that FMT can be an effective treatment for refractory C. difficile infection in pediatrics. Long-term safety and efficacy need to be studied.
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Clostridium difficile eradication using fecal microbiota transplantation (FMT) has been successful in adults but little information is available in pediatrics. We report 6 pediatric patients with refractory C. difficile cured by FMT with no recurrences to date. Our results demonstrate that FMT can be an effective treatment for refractory C. difficile infection in pediatrics. Long-term safety and efficacy need to be studied.
Key concepts: Clostridium difficile, Fecal bacteriotherapy, Refractory (planetary science), Feces, Medicine, C difficile, Transplantation, Microbiology