2003•Transplantation and Cellular TherapyOpen access

91 T-cell apoptosis following non-myeloablative hematopoietic cell transplantation (HCT)

Vikas Bhushan, Katherine Singleton, Ming-Tseh Lin, Laura Tabellini, Haydar Frangoul, Anand C. Damodaran, J. A. Hansen

Abstract

Presentations -Session IMM.CBA myeloid leukemia cell line did not block an effective GVL response, despite reducing lethal GVHD.These results demonstrate that donor CD4+CD25 + T ceils infused early posttransplant can control the full development of GVItD without sacrificing a sufficient GVL effect.

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Key concepts: Medicine, Hematopoietic cell, Apoptosis, Transplantation, Haematopoiesis, Oncology, Hematopoietic stem cell transplantation, Cancer research