Bone formation following dental implant placement with augmentation materials at dehiscence defects in dogs : pilot study

PURPOSE: Guided bone regeneration(GBR) has emerged as a treatment in the management of osseous defects associated with dental implants. But several studies have reported different degrees of success of guided bone regeneration, depending upon the type of barrier selected, presence or absence of an underlying graft material, types of graft material, feasibility of technique, and clinician's preference. The aim of the present study was to evaluate bone formation following dental implant placement with augmentation materials at dehiscence defects in dogs. MATERIAL AND METHODS: Standardized buccal dehiscence defects(3x5 mm) were surgically 2 Mongrel dog's mandibles, each 8 SLA surface, 8 anodizing surface implants. Each buccal dehiscence defect received flap surgery only(no treatment, control), Cytoflex(R) membrane only, Resolut XT(R) membrane only, Resolut XT(R)+Osteon(TM). Animals were sacrificed at 8 weeks postsurgery and block sections were harvested for histologic analysis. RESULTS: All experimental group resulted in higher bone formation than control. Resolut XT(R)+Osteon(TM) group resulted appeared highest defect resolution. There was no difference between SLA and anodizing surface, nonresorbable and resorbable membrane. CONCLUSION: GBR results in rapid and clinically relevant bone closure on dehiscence defects of the dental implants.