2003The Journal of General PhysiologyOpen access

Spermine Is Fit to Block Inward Rectifier (Kir) Channels

Peter R. Stanfield, Michael J. Sutcliffe

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Abstract

Molecular biology has shown there to be a great diversity of potassium channel isoforms. Among the simplest structurally are the inward rectifier potassium channel, KCNJ gene family. These channels are open in the region of the resting potential, a potential that they therefore help to determine.

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What this paper is about

Molecular biology has shown there to be a great diversity of potassium channel isoforms. Among the simplest structurally are the inward rectifier potassium channel, KCNJ gene family. These channels are open in the region of the resting potential, a potential that they therefore help to determine.

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Available abstract

Molecular biology has shown there to be a great diversity of potassium channel isoforms. Among the simplest structurally are the inward rectifier potassium channel, KCNJ gene family. These channels are open in the region of the resting potential, a potential that they therefore help to determine.

Key concepts: Inward-rectifier potassium ion channel, Potassium channel, Spermine, Potassium, Membrane potential, Chemistry, Biophysics, Ion channel

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