2002•Biochemical PharmacologyRequires access

Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance

Emma Månsson, Emma Flordal, Jan Liliemark, T. Spasokoukotskaja, Howard L. Elford, Svetlana Bajalica‐Lagercrantz, Staffan Eriksson, Freidoun Albertioni

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Key concepts: Deoxycytidine kinase, Ribonucleotide reductase, Cladribine, Deoxyadenosine, Clofarabine, Cell culture, Nucleoside, Fludarabine