2011•Bioorganic & Medicinal Chemistry LettersOpen access

Biaryl analogues of teriflunomide as potent DHODH inhibitors

Montse Erra, Imma Moreno, Jordi Sanahuja, Míriam Andrés, Raquel F. Reinoso, Estrella Lozoya, Pilar Pizcueta, Núria Godessart, Julio C. Castro‐Palomino

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Key concepts: Dihydroorotate dehydrogenase, Teriflunomide, Chemistry, In vivo, Leflunomide, Pharmacology, Peripheral blood mononuclear cell, Structure–activity relationship

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