1979•Japanese Heart JournalOpen access

Vectorcardiographical Studies on Spontaneous and Experimental "Myocardial Infarction" in Rats

Yukio Yamori, Michiya Ohtaka, Masahiro Kihara, Yasuo Nara, Ryoichi Horie, Akira Ooshima

Abstract

(1) In Experiment 2, the deformity or irregularity of QRS vector in VCG was ascertained to correspond to myocardial necrosis and fibrosis(2) In Experiment 1, myocardial lesions of SHRSP could be detected vectorcardiographically about 1 year of age. And, such myocardial lesions as diffuse fibrosis developed progressively but rather gradually, compared with "sudden onset" of the artificial myocardial infarction as demonstrated in Experiment 2Thus, vectorcardiographical or pathological study on the heart of SHRSP and its comparison with the surgically induced myocardial infarciton in WK demonstrated that the heart of old SHRSP could be used as the model of myocardial infarction

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Key concepts: Myocardial infarction, Medicine, Myocardial fibrosis, Cardiology, Internal medicine, Pathological, QRS complex, Fibrosis