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D‐Penicillamine in rheumatoid arthritis

Jack Zuckner, Robert H. Ramsey, Robert W. Dorner, George E. Gantner

Open publisher page 77 citations

Abstract

Abstract D‐penicillamine was administered to 15 patients with rheumatoid arthritis. A fall in the titer of rheumatoid factor was demonstrated in all patients. The sedimentation rate decreased in most patients. There was no consistent alteration in immunoglobulins A, G or M or in lymphocyte transformation attributable to penicillamine. Ceruloplasmin serum levels were lowered significantly in 7 patients. Clinical improvement in the arthritis resulted in 10 patients.

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What this paper is about

Abstract D‐penicillamine was administered to 15 patients with rheumatoid arthritis. A fall in the titer of rheumatoid factor was demonstrated in all patients. The sedimentation rate decreased in most patients. There was no consistent alteration in immunoglobulins A, G or M or in lymphocyte transformation attributable to penicillamine. Ceruloplasmin serum levels were lowered significantly in 7 patients. Clinical improvement in the arthritis resulted in 10 patients.

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OpenAlex reports 77 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Abstract D‐penicillamine was administered to 15 patients with rheumatoid arthritis. A fall in the titer of rheumatoid factor was demonstrated in all patients. The sedimentation rate decreased in most patients. There was no consistent alteration in immunoglobulins A, G or M or in lymphocyte transformation attributable to penicillamine. Ceruloplasmin serum levels were lowered significantly in 7 patients. Clinical improvement in the arthritis resulted in 10 patients.

Key concepts: Penicillamine, Rheumatoid arthritis, Medicine, Ceruloplasmin, Erythrocyte sedimentation rate, Rheumatoid factor, Titer, Internal medicine

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