1980Annals of Internal MedicineRequires access

"Phosphorus" or "Phosphate"

Donald S. Young

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Abstract

Editorial Notes1 October 1980"Phosphorus" or "Phosphate"DONALD S. YOUNG, M.B., PH.D.DONALD S. YOUNG, M.B., PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-93-4-631_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPhosphate is one of the most commonly measured constituents of serum, but because it is one of the components analyzed by most multitest chemical analyzers in the clinical laboratory, the measurement is rarely of much clinical use. The causes of hyperphosphatemia and hypophosphatemia recently have been reviewed by Slatopolsky and associates (1) and Fitzgerald (2).Phosphorus is present mainly in living organisms as inorganic phosphate or as organic phosphate esters. About 80% of the approximately 750 g of phosphorus in the adult human occurs in the bone matrix in insoluble calcium salts. Up to 15% of the total phosphate is...References1. SLATOPOLSKYRUTHERFORDROSENBAUMMARTINHRUSKA EWRKK. Hyperphosphatemia. Clin Nephrol. 1977;7:138-46. MedlineGoogle Scholar2. FITZGERALD F. Clinical hypophosphatemia. Annu Rev Med. 1978;29:177-89. CrossrefMedlineGoogle Scholar3. KNOCHEL J. The pathophysiology and clinical characteristics of severe hypophosphatemia. Arch Intern Med. 1977;137:203-20. CrossrefMedlineGoogle Scholar4. WALSER M. Ion association: VI. Interactions between calcium, magnesium, inorganic phosphate, citrate and protein in normal human plasma. J Clin Invest. 1961;40:723-30. CrossrefMedlineGoogle Scholar5. LENTZBROWNKJELLSTRAND RDC. Treatment of severe hypophosphatemia. Ann Intern Med. 1978;89:941-4. LinkGoogle Scholar6. TIETZ N. Electrolytes. In: TIETZ NW, ed. Fundamentals of Clinical Chemistry. 2nd ed. Philadelphia: W. B. Saunders Co.; 1976:873-944. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Mayo Clinic Rochester, Minnesota PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPhosphorus, phosphorous, and phosphateFluid and Electrolyte DisordersHypophosphatemiaToxic Oxygen Products in ShockThe Effects of High-Dose Corticosteroids in Patients with Septic Shock 1 October 1980Volume 93, Issue 4Page: 631-631KeywordsAdultsBoneCalciumClinical laboratoriesPhosphatesPhosphorusSalts Issue Published: 1 October 1980 PDF downloadLoading ...

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Editorial Notes1 October 1980"Phosphorus" or "Phosphate"DONALD S. YOUNG, M.B., PH.D.DONALD S. YOUNG, M.B., PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-93-4-631_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPhosphate is one of the most commonly measured constituents of serum, but because it is one of the components analyzed by most multitest chemical analyzers in the clinical laboratory, the measurement is rarely of much clinical use. The causes of hyperphosphatemia and hypophosphatemia recently have been reviewed by Slatopolsky and associates (1) and Fitzgerald (2).Phosphorus is present mainly in living organisms as inorganic phosphate or as organic phosphate esters. About 80% of the approximately 750 g of phosphorus in the adult human occurs in the bone matrix in insoluble calcium salts. Up to 15% of the total phosphate is...References1. SLATOPOLSKYRUTHERFORDROSENBAUMMARTINHRUSKA EWRKK. Hyperphosphatemia. Clin Nephrol. 1977;7:138-46. MedlineGoogle Scholar2. FITZGERALD F. Clinical hypophosphatemia. Annu Rev Med. 1978;29:177-89. CrossrefMedlineGoogle Scholar3. KNOCHEL J. The pathophysiology and clinical characteristics of severe hypophosphatemia. Arch Intern Med. 1977;137:203-20. CrossrefMedlineGoogle Scholar4. WALSER M. Ion association: VI. Interactions between calcium, magnesium, inorganic phosphate, citrate and protein in normal human plasma. J Clin Invest. 1961;40:723-30. CrossrefMedlineGoogle Scholar5. LENTZBROWNKJELLSTRAND RDC. Treatment of severe hypophosphatemia. Ann Intern Med. 1978;89:941-4. LinkGoogle Scholar6. TIETZ N. Electrolytes. In: TIETZ NW, ed. Fundamentals of Clinical Chemistry. 2nd ed. Philadelphia: W. B. Saunders Co.; 1976:873-944. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Mayo Clinic Rochester, Minnesota PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPhosphorus, phosphorous, and phosphateFluid and Electrolyte DisordersHypophosphatemiaToxic Oxygen Products in ShockThe Effects of High-Dose Corticosteroids in Patients with Septic Shock 1 October 1980Volume 93, Issue 4Page: 631-631KeywordsAdultsBoneCalciumClinical laboratoriesPhosphatesPhosphorusSalts Issue Published: 1 October 1980 PDF downloadLoading ...

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Editorial Notes1 October 1980"Phosphorus" or "Phosphate"DONALD S. YOUNG, M.B., PH.D.DONALD S. YOUNG, M.B., PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-93-4-631_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPhosphate is one of the most commonly measured constituents of serum, but because it is one of the components analyzed by most multitest chemical analyzers in the clinical laboratory, the measurement is rarely of much clinical use. The causes of hyperphosphatemia and hypophosphatemia recently have been reviewed by Slatopolsky and associates (1) and Fitzgerald (2).Phosphorus is present mainly in living organisms as inorganic phosphate or as organic phosphate esters. About 80% of the approximately 750 g of phosphorus in the adult human occurs in the bone matrix in insoluble calcium salts. Up to 15% of the total phosphate is...References1. SLATOPOLSKYRUTHERFORDROSENBAUMMARTINHRUSKA EWRKK. Hyperphosphatemia. Clin Nephrol. 1977;7:138-46. MedlineGoogle Scholar2. FITZGERALD F. Clinical hypophosphatemia. Annu Rev Med. 1978;29:177-89. CrossrefMedlineGoogle Scholar3. KNOCHEL J. The pathophysiology and clinical characteristics of severe hypophosphatemia. Arch Intern Med. 1977;137:203-20. CrossrefMedlineGoogle Scholar4. WALSER M. Ion association: VI. Interactions between calcium, magnesium, inorganic phosphate, citrate and protein in normal human plasma. J Clin Invest. 1961;40:723-30. CrossrefMedlineGoogle Scholar5. LENTZBROWNKJELLSTRAND RDC. Treatment of severe hypophosphatemia. Ann Intern Med. 1978;89:941-4. LinkGoogle Scholar6. TIETZ N. Electrolytes. In: TIETZ NW, ed. Fundamentals of Clinical Chemistry. 2nd ed. Philadelphia: W. B. Saunders Co.; 1976:873-944. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Mayo Clinic Rochester, Minnesota PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPhosphorus, phosphorous, and phosphateFluid and Electrolyte DisordersHypophosphatemiaToxic Oxygen Products in ShockThe Effects of High-Dose Corticosteroids in Patients with Septic Shock 1 October 1980Volume 93, Issue 4Page: 631-631KeywordsAdultsBoneCalciumClinical laboratoriesPhosphatesPhosphorusSalts Issue Published: 1 October 1980 PDF downloadLoading ...

Key concepts: Hypophosphatemia, Hyperphosphatemia, Phosphate, Medicine, Phosphorus, Calcium, Inorganic phosphate, Internal medicine

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