1980•Hormone and Metabolic ResearchRequires access

Effect of Thyroxine on the Hepatic Glycogen and Glucose-6-Phosphatase Activity of Developing Rats

A. Paul, Anju Dhar

Abstract

The influence of exogenous thyroxine was studied on the hepatic glycogen content and glucose-6-phosphatase activity of rats of different age groups. The glycogen content and glucose-6-phosphatase activity were found to be decreased in the livers of 5, 15, 30 and 60-day-old rats after thyroxine treatment. In normal rats of 5, 15, 30 and 60-day-old, a gradual rise in both the hepatic glycogen content and glucose-6-phosphatase activity was noted as the age advanced from immature to adult.

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Key concepts: Internal medicine, Endocrinology, Glycogen, Glucose 6-phosphatase, Phosphatase, Chemistry, Alkaline phosphatase, Enzyme