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Hemoglobin S and Some Other Hemoglobinopathies in Eti-Turks

Çiğdem Altay, Sevgi Yetgin, S. Ouml zsoylu, A. Kutsal

Abstract

Frequencies of various hemoglobinopathies were examined in a total of 1,922 individuals of Eti-Turk origin by electrophoretical techniques. Hemoglobin A2 (Hb A2) and hemoglobin F (Hb F) determinations were also performed in 651 and 1,642 cases, respectively. Mean hemoglobin S (Hb S) frequency was found to be 15.3%. Variations among the different age groups were insignificant. Hemoglobin E (Hb E) and beta-thalassemia frequencies wer 0.47 and 1.23%, respectively. Hemoglobin Hacettepe and hemoglobin D were found once. Red cell glucose-6-phosphate dehydrogenase (G6PD) deficiency was found in 6.5% of males.

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Key concepts: Hemoglobin, Hemoglobin A2, Thalassemia, Hemoglobin s, Hemoglobin F, Hemoglobinopathy, Hemoglobin A, Red Cell