Host–guest chemistry of calixarene capsules
JULIUS JUN. REBEK
Abstract
JULIUS JUN. REBEK
Abstract
Reversible encapsulation is one of the more recent forms of molecular recognition. Small molecule targets are completely surrounded by larger molecular assemblies and steric barriers keep the guest from escaping the host. Calix[4]arenes make useful modules for capsule construction and the review traces their history. Applications in physical organic chemistry, materials science and spectroscopy are described.
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Reversible encapsulation is one of the more recent forms of molecular recognition. Small molecule targets are completely surrounded by larger molecular assemblies and steric barriers keep the guest from escaping the host. Calix[4]arenes make useful modules for capsule construction and the review traces their history. Applications in physical organic chemistry, materials science and spectroscopy are described.
Key concepts: Calixarene, Steric effects, Host–guest chemistry, Chemistry, Molecule, Host (biology), Molecular recognition, Nanotechnology