ScholarLens Back to search
2008•Annals of the New York Academy of SciencesRequires access

Mesothelioma and Environmental Exposure

Csaba Varga, Katalin Szendi

Open publisher page 3 citations

Abstract

A novel animal model was developed to study the direct exposure of mesothelial cells to crocidolite and chrysotile asbestos fibers. Chemically pure and pretreated Union Internationale Centre le Cancer (UICC) samples were implanted into a peritoneal envelope (Kertai's fold) of Wistar rats. Following the 12-month exposure, lack of mesothelioma induction was detected in all groups. Results suggest that the mechanism of mesothelioma formation is not a consequence of peritoneal physical exposure to the fibers.

About this research paper

What this paper is about

A novel animal model was developed to study the direct exposure of mesothelial cells to crocidolite and chrysotile asbestos fibers. Chemically pure and pretreated Union Internationale Centre le Cancer (UICC) samples were implanted into a peritoneal envelope (Kertai's fold) of Wistar rats. Following the 12-month exposure, lack of mesothelioma induction was detected in all groups. Results suggest that the mechanism of mesothelioma formation is not a consequence of peritoneal physical exposure to the fibers.

Why it matters

OpenAlex reports 3 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

A novel animal model was developed to study the direct exposure of mesothelial cells to crocidolite and chrysotile asbestos fibers. Chemically pure and pretreated Union Internationale Centre le Cancer (UICC) samples were implanted into a peritoneal envelope (Kertai's fold) of Wistar rats. Following the 12-month exposure, lack of mesothelioma induction was detected in all groups. Results suggest that the mechanism of mesothelioma formation is not a consequence of peritoneal physical exposure to the fibers.

Key concepts: Mesothelioma, Chrysotile, Mesothelial Cell, Peritoneal mesothelioma, Asbestos, Mesothelium, Pathology, Medicine

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Mesothelioma and Environmental Exposure — Research Paper | ScholarLens