2014International Journal of Biomedical and Advance ResearchOpen access

Myoepithelioma of Parotid: A diagnostic dilemma

Puja Sharma, Pawan Singh, Shivani Kalhan, Shilpa Garg, Manmeet Kaur Gill, Ashok Sangwaiya

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Abstract

Myoepitheliomas are rare benign salivary gland neoplasms which originate from ectodermally derived contractile smooth muscle cells i.e. myoepithelial cells which lack ductal differentiation. They account for only 1-1.5% of all salivary gland neoplasms. Myoepithelioma was considered as a variant of Pleomorphic adenoma in the past, but since 1991 it has been considered as a separate clinical entity by WHO.Their preoparative diagnosis on cytologic features is possible but is often difficult. Here we are discussing a case of parotid swelling which was cytologically diagnosed as basal cell adenoma but on histopathological and immunohistochemical studies, it was proved as a case of myoepithelioma.

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What this paper is about

Myoepitheliomas are rare benign salivary gland neoplasms which originate from ectodermally derived contractile smooth muscle cells i.e. myoepithelial cells which lack ductal differentiation. They account for only 1-1.5% of all salivary gland neoplasms. Myoepithelioma was considered as a variant of Pleomorphic adenoma in the past, but since 1991 it has been considered as a separate clinical entity by WHO.Their preoparative diagnosis on cytologic features is possible but is often difficult. Here we are discussing a case of parotid swelling which was cytologically diagnosed as basal cell adenoma but on histopathological and immunohistochemical studies, it was proved as a case of myoepithelioma.

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Available abstract

Myoepitheliomas are rare benign salivary gland neoplasms which originate from ectodermally derived contractile smooth muscle cells i.e. myoepithelial cells which lack ductal differentiation. They account for only 1-1.5% of all salivary gland neoplasms. Myoepithelioma was considered as a variant of Pleomorphic adenoma in the past, but since 1991 it has been considered as a separate clinical entity by WHO.Their preoparative diagnosis on cytologic features is possible but is often difficult. Here we are discussing a case of parotid swelling which was cytologically diagnosed as basal cell adenoma but on histopathological and immunohistochemical studies, it was proved as a case of myoepithelioma.

Key concepts: Myoepithelial cell, Myoepithelioma, Pleomorphic adenoma, Parotid gland, Pathology, Salivary gland, Immunohistochemistry, Medicine

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