Myoepithelioma of Parotid: A diagnostic dilemma
Puja Sharma, Pawan Singh, Shivani Kalhan, Shilpa Garg, Manmeet Kaur Gill, Ashok Sangwaiya
Abstract
Puja Sharma, Pawan Singh, Shivani Kalhan, Shilpa Garg, Manmeet Kaur Gill, Ashok Sangwaiya
Abstract
Myoepitheliomas are rare benign salivary gland neoplasms which originate from ectodermally derived contractile smooth muscle cells i.e. myoepithelial cells which lack ductal differentiation. They account for only 1-1.5% of all salivary gland neoplasms. Myoepithelioma was considered as a variant of Pleomorphic adenoma in the past, but since 1991 it has been considered as a separate clinical entity by WHO.Their preoparative diagnosis on cytologic features is possible but is often difficult. Here we are discussing a case of parotid swelling which was cytologically diagnosed as basal cell adenoma but on histopathological and immunohistochemical studies, it was proved as a case of myoepithelioma.
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Myoepitheliomas are rare benign salivary gland neoplasms which originate from ectodermally derived contractile smooth muscle cells i.e. myoepithelial cells which lack ductal differentiation. They account for only 1-1.5% of all salivary gland neoplasms. Myoepithelioma was considered as a variant of Pleomorphic adenoma in the past, but since 1991 it has been considered as a separate clinical entity by WHO.Their preoparative diagnosis on cytologic features is possible but is often difficult. Here we are discussing a case of parotid swelling which was cytologically diagnosed as basal cell adenoma but on histopathological and immunohistochemical studies, it was proved as a case of myoepithelioma.
Key concepts: Myoepithelial cell, Myoepithelioma, Pleomorphic adenoma, Parotid gland, Pathology, Salivary gland, Immunohistochemistry, Medicine