2002•New England Journal of MedicineRequires access

Helicobacter pylori Infection

Sebastian Suerbaum, Pierre Michetti

Abstract

H. pylori is one of the most common bacterial infections in human beings, and its discovery 20 years ago altered the diagnosis and treatment of gastroduodenal disease. This review considers current knowledge about the epidemiology and transmission of H. pylori, as well as the role of this infectious agent in the pathogenesis of upper gastrointestinal tract disease. Diagnostic approaches, indications for therapy, and measures of therapeutic efficacy are reviewed.

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Key concepts: Medicine, Helicobacter pylori, Disease, Epidemiology, Helicobacter pylori infection, Pathogenesis, Helicobacter Infections, Infectious disease (medical specialty)