2000•American Journal of OphthalmologyOpen access

Rhegmatogenous retinal detachment in retinoblastoma patients undergoing chemoreduction and cryotherapy

Scott Anagnoste, Ingrid Ursula Scott, Timothy G. Murray, Deborah L. Kramer, Stuart Toledano

Abstract

PURPOSE: To report the development of rhegmatogenous retinal detachment, with the retinal break adjacent to a cryotherapy scar, in three patients undergoing systemic chemotherapy for intraocular retinoblastoma. METHOD: Case series. RESULTS: Three patients with intraocular retinoblastoma were referred after poor response to systemic chemotherapy and local cryotherapy; three eyes of these three patients were noted to have rhegmatogenous retinal detachment and active retinoblastoma, with retinal breaks adjacent to cryotherapy scars. CONCLUSION: Rhegmatogenous retinal detachment may result from retinal necrosis associated with cryotherapy in the setting of intraocular retinoblastoma treated with systemic chemotherapy and local cryotherapy.

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Key concepts: Cryotherapy, Retinal detachment, Medicine, Retinoblastoma, Retinal, Ophthalmology, Chemotherapy, Cryosurgery