2001•CellOpen access

Cholesterol Modification of Sonic Hedgehog Is Required for Long-Range Signaling Activity and Effective Modulation of Signaling by Ptc1

Paula Lewis, Matthew Dunn, Jill A. McMahon, Malcolm Logan, James F. Martin, Benoit St‐Jacques, Andrew P. McMahon

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Key concepts: Sonic hedgehog, Biology, Signal transduction, Cell biology, Hedgehog signaling pathway, Patched, Hedgehog, Smoothened

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Cholesterol Modification of Sonic Hedgehog Is Required for Long-Range Signaling Activity and Effective Modulation of Signaling by Ptc1 — Research Paper | ScholarLens