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2013•Investigational New DrugsRequires access

Sustained inhibition of deacetylases is required for the antitumor activity of the histone deactylase inhibitors panobinostat and vorinostat in models of colorectal cancer

Peter M. Wilson, Melissa J. LaBonte, Shelby C. Martin, Stephanie T. Kuwahara, Anthony B. El-Khoueiry, Heinz‐Josef Lenz, Robert D. Ladner

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Key concepts: Panobinostat, Vorinostat, Colorectal cancer, Histone, Cancer research, Pharmacology, Histone deacetylase inhibitor, Medicine

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Sustained inhibition of deacetylases is required for the antitumor activity of the histone deactylase inhibitors panobinostat and vorinostat in models of colorectal cancer — Research Paper | ScholarLens