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2014•Nature CommunicationsOpen access

The covalent modifier Nedd8 is critical for the activation of Smurf1 ubiquitin ligase in tumorigenesis

Ping Xie, Minghua Zhang, Shan He, Kefeng Lu, Yuhan Chen, Guichun Xing, Yiming Lu, Ping Liu, Li Yang, Shaoxia Wang, Nan Chai, Jiawei Wu, Haiteng Deng, Hongrui Wang, Yu Cao, Fei Zhao, Yu Cui, Jian Wang, Fuchu He, Lingqiang Zhang

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Key concepts: Neddylation, NEDD8, Ubiquitin ligase, Ubiquitin, DNA ligase, Cell biology, Cullin, Chemistry

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The covalent modifier Nedd8 is critical for the activation of Smurf1 ubiquitin ligase in tumorigenesis — Research Paper | ScholarLens