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2009•International Archives of Allergy and Applied ImmunologyRequires access

Lymphocyte Transformation Induced by Autologous Cells

Dana H. Bovbjerg, V.A. Wang, R. Schwab, K.S. Lebenger, G W Siskind, Marc E. Weksler

Open publisher page 6 citations

Abstract

The autologous mixed lymphocyte reaction (AMLR) is impaired in patients with a number of diseases associated with abnormal immunoregulation. Since allergic disorders are also associated with abnormal immunoregulation, we assessed the AMLR in individuals with a history of ragweed hayfever. Lymphocytes from allergic subjects had a lower AMLR than nonallergic controls by rank order analysis. These results support the association of abnormal in vivo immunoregulation with reduced AMLR.

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What this paper is about

The autologous mixed lymphocyte reaction (AMLR) is impaired in patients with a number of diseases associated with abnormal immunoregulation. Since allergic disorders are also associated with abnormal immunoregulation, we assessed the AMLR in individuals with a history of ragweed hayfever. Lymphocytes from allergic subjects had a lower AMLR than nonallergic controls by rank order analysis. These results support the association of abnormal in vivo immunoregulation with reduced AMLR.

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OpenAlex reports 6 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The autologous mixed lymphocyte reaction (AMLR) is impaired in patients with a number of diseases associated with abnormal immunoregulation. Since allergic disorders are also associated with abnormal immunoregulation, we assessed the AMLR in individuals with a history of ragweed hayfever. Lymphocytes from allergic subjects had a lower AMLR than nonallergic controls by rank order analysis. These results support the association of abnormal in vivo immunoregulation with reduced AMLR.

Key concepts: Ragweed, Immunology, Mixed lymphocyte reaction, Allergic reaction, In vivo, Lymphocyte, Medicine, Immune system

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