2014•Advances in intelligent systems research/Advances in Intelligent Systems ResearchOpen access

TFCM Induced Vasodilation of Isolated Rat Thoracic Aorta

Mei Lv, Bin Li, Wenjun Shi, Junchao Zou, Xiaowei Fei, Zile Yu, Yibing Bu, Shiyue Tang

Open full text 0 citations

Abstract

By the way of isolated vessel perfusion, the direct effect of TFCM on blood vessel contraction was observed and its influence on blood vessel contraction caused by phenylephrine (PE) or potassium chloride, intracellular calcium releasing and extracellular calcium inflowing.TFCM did not directly relax or contract vascular rings, but TFCM could significantly inhibit the contraction of the vascular rings caused by phenylephrine (PE), and potassium chloride (compare with those of control, P>0.05), and the same inhibition to the contraction caused by intracellular calcium releasing and extracellular calcium inflowing (compare with those of control, P<0.05).TFCM could inhibit the contraction of vascular rings caused by phenylephrine and potassium chloride, whose possible mechanism was to inhibit intracellular calcium releasing and extracellular calcium inflowing.

Open-access reader

About this research paper

What this paper is about

By the way of isolated vessel perfusion, the direct effect of TFCM on blood vessel contraction was observed and its influence on blood vessel contraction caused by phenylephrine (PE) or potassium chloride, intracellular calcium releasing and extracellular calcium inflowing.TFCM did not directly relax or contract vascular rings, but TFCM could significantly inhibit the contraction of the vascular rings caused by phenylephrine (PE), and potassium chloride (compare with those of control, P>0.05), and the same inhibition to the contraction caused by intracellular calcium releasing and extracellular calcium inflowing (compare with those of control, P<0.05).TFCM could inhibit the contraction of vascular rings caused by phenylephrine and potassium chloride, whose possible mechanism was to inhibit intracellular calcium releasing and extracellular calcium inflowing.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

By the way of isolated vessel perfusion, the direct effect of TFCM on blood vessel contraction was observed and its influence on blood vessel contraction caused by phenylephrine (PE) or potassium chloride, intracellular calcium releasing and extracellular calcium inflowing.TFCM did not directly relax or contract vascular rings, but TFCM could significantly inhibit the contraction of the vascular rings caused by phenylephrine (PE), and potassium chloride (compare with those of control, P>0.05), and the same inhibition to the contraction caused by intracellular calcium releasing and extracellular calcium inflowing (compare with those of control, P<0.05).TFCM could inhibit the contraction of vascular rings caused by phenylephrine and potassium chloride, whose possible mechanism was to inhibit intracellular calcium releasing and extracellular calcium inflowing.

Key concepts: Phenylephrine, Contraction (grammar), Calcium, Extracellular, Vasodilation, Chemistry, Calcium in biology, Potassium

Related papers

Back to paper searchBrowse research topicsOriginal source
TFCM Induced Vasodilation of Isolated Rat Thoracic Aorta — Research Paper | ScholarLens