2013•Russian Journal of Physical Chemistry ARequires access

Determining the thermodynamic melting parameters of sulfamethoxazole, trimethoprim, urea, nicodin, and their double eutectics by differential scanning calorimetry

E. V. Agafonova, Yu. V. Moshchenskii, Михаил Лукич Ткаченко

Abstract

The literature data on the thermodynamic melting characteristics of sulfamethoxazole, urea, trimethoprim, and nicodin are analyzed for individual compounds. Their enthalpies and melting points, either individually or in the composition of eutectics, are found by means of DSC. The entropies of fusion and the cryoscopic constants of individual compounds are calculated.

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Key concepts: Enthalpy of fusion, Eutectic system, Differential scanning calorimetry, Trimethoprim, Melting point, Fusion, Chemistry, Urea