2003•NeuroImageRequires access

Quantitative assessment of P-glycoprotein function in the rat blood–brain barrier by distribution volume of [11C]verapamil measured with PET

Joost Bart, Antoon T. M. Willemsen, Harry J.M. Groen, Winette T.A. van der Graaf, Theodora D Wegman, Willem Vaalburg, Elisabeth G.E. de Vries, N. Harry Hendrikse

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Key concepts: Verapamil, P-glycoprotein, Kinetics, Chemistry, Blood–brain barrier, Blood sampling, Positron emission tomography, Distribution (mathematics)