2003•LeukemiaOpen access

Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 Concerted Action BMH4-CT98-3936

Jacques J. M. van Dongen, Anton W. Langerak, Monika Brüggemann, Paul Evans, Michael Hummel, F. Louise Lavender, Éric Delabesse, Frédéric Davi, Ed Schuuring, Ramón García‐Sánz, J. Han van Krieken, J Droese, David González de Castro, Christian Bastard, Helen White, Marcel Spaargaren, Marcos González, A Parreira, J L Smith, Gareth J. Morgan, Michael Kneba, Elizabeth Macintyre

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Key concepts: Multiplex ligation-dependent probe amplification, T-cell receptor, Heteroduplex, Biology, Molecular biology, Polymerase chain reaction, Minimal residual disease, Immunoglobulin heavy chain